What should I avoid with Helicobacter pylori?

Foods that increase the risk of gastritis – A person may be more likely to develop gastritis if they consume:

red meatsprocessed meatsfoods that are pickled, dried, salted, or smokedsalty foodsfatty foodsalcohol

Studies have shown that salty and fatty foods, for example, can change the stomach lining. High-salt diets can alter the cells within the stomach, making them more prone to H. pylori infection. A high intake of alcohol can also contribute to stomach inflammation and make symptoms worse.

  1. It can also cause erosion of the stomach lining.
  2. To help prevent or manage gastritis, try : Quitting smoking : Smoking increases the risk of inflammation and mouth, esophageal, and stomach cancers.
  3. Reducing stress : High levels of stress can trigger stomach acid production, which can worsen symptoms and inflammation.

Checking any medications : Regularly using NSAIDs can increase the risk of damage to the stomach lining, which can trigger or worsen symptoms of gastritis. Aspirin, ibuprofen, and naproxen are all examples of NSAIDs. Gastritis is a common digestive problem.

What is the best food to cure Helicobacter pylori?

What foods heal the stomach lining? – Some of the highly recommended foods promoting gut healing include probiotics like fermented vegetables, yogurt and kombucha, salmon, leafy greens, bananas, bone broth, pineapple, kiwi, coconut milk, broccoli, and green tea.

Can I drink coffee with H. pylori?

Eat smaller meals more often, instead of three larger meals a day. Avoid eating foods that bother you. And avoid things that can irritate your stomach lining, such as black pepper or items with caffeine (soda, tea, coffee, and chocolate).

Is milk bad for pylori?

Conclusions – High presence of antibiotic-resistant strains of H. pylori suggest that milk and dairy samples may be the sources of bacteria that can cause severe infection. Our findings should raise awareness about antibiotic resistance in H. pylori strains in Iran.

What kills Helicobacter fast?

Helicobacter pylori ( H. pylori ) is a type of bacteria. These germs can enter your body and live in your digestive tract. After many years, they can cause sores, called ulcers, in the lining of your stomach or the upper part of your small intestine. For some people, an infection can lead to stomach cancer,

  • Infection with H.
  • Pylori is common.
  • About two-thirds of the world’s population has it in their bodies.
  • For most people, it doesn’t cause ulcers or any other symptoms.
  • If you do have problems, there are medicines that can kill the germs and help sores heal.
  • As more of the world gets access to clean water and sanitation, fewer people than before are getting the bacteria,

With good health habits, you can protect yourself and your children from H. pylori, For decades, doctors thought people got ulcers from stress, spicy foods, smoking, or other lifestyle habits. But when scientists discovered H. pylori in 1982, they found that the germs were the cause of most stomach ulcers,

After H. pylori enters your body, it attacks the lining of your stomach, which usually protects you from the acid your body uses to digest food. Once the bacteria have done enough damage, acid can get through the lining, which leads to ulcers. These may bleed, cause infections, or keep food from moving through your digestive tract.

You can get H. pylori from food, water, or utensils. It’s more common in countries or communities that lack clean water or good sewage systems. You can also pick up the bacteria through contact with the saliva or other body fluids of infected people. Many people get H.

  1. Pylori during childhood, but adults can get it, too.
  2. The germs live in the body for years before symptoms start, but most people who have it will never get ulcers.
  3. Doctors aren’t sure why only some people get ulcers after an infection.
  4. If you have an ulcer, you may feel a dull or burning pain in your belly.

It may come and go, but you’ll probably feel it most when your stomach is empty, such as between meals or in the middle of the night. It can last for a few minutes or for hours. You may feel better after you eat, drink milk, or take an antacid. Other signs of an ulcer include:

Bloating BurpingNot feeling hungry Nausea Vomiting Weight loss for no clear reason

Ulcers can bleed into your stomach or intestines, which can be dangerous to your health. Get medical help right away if you have any of these symptoms:

Stool that is bloody, dark red, or black Trouble breathing Dizziness or fainting Feeling very tired for no reasonPale skin colorVomit that has blood or looks like coffee groundsSevere, sharp stomach pain

It’s not common, but H. pylori infection can cause stomach cancer, The disease has few symptoms at first, such as heartburn. Over time, you may notice:

Belly pain or swellingNauseaNot feeling hungry Feeling full after you eat just a small amount Vomiting Weight loss for no reason

If you don’t have symptoms of an ulcer, your doctor probably won’t test you for H. pylori, But if you have them now or have in the past, it’s best to get tested. Medicines like nonsteroidal anti-inflammatory drugs ( NSAIDs ) can also damage your stomach lining, so it’s important to find out what’s causing your symptoms so you can get the right treatment.

Tests of your blood and stool, which can help find an infection Urea breath test, You’ll drink a special liquid that has a substance called urea. Then you’ll breathe into a bag, which your doctor will send to a lab for testing. If you have H. pylori, the bacteria will change the urea in your body into carbon dioxide, and lab tests will show that your breath has higher than normal levels of the gas.

To look more closely at your ulcers, your doctor may use:

Upper gastrointestinal endoscopy, In a hospital, a doctor will use a tube with a small camera, called an endoscope, to look down your throat and into your stomach and the upper part of your small intestine. The procedure may also be used to collect a sample that will be examined for the presence of the bacteria. You may be asleep or awake during the procedure, but you’ll get medicine to make you more comfortable. Upper GI tests, In a hospital, you’ll drink a liquid that has a substance called barium, and your doctor will give you an X-ray. The fluid coats your throat and stomach and makes them stand out clearly on the image. Computed tomography (CT) scan. It’s a powerful X-ray that makes detailed pictures of the inside of your body.

If you have H. pylori, your doctor may also test you for stomach cancer. This includes:

Physical examBlood tests to check for anemia, when your body doesn’t have enough red blood cells, It could happen if you have a tumor that bleeds. Fecal occult blood test, which checks your stool for blood that’s not visible to the naked eye Endoscopy Biopsy, when a doctor takes a small piece of tissue from your stomach to look for signs of cancer, Your doctor may do this during an endoscopy.Tests that make detailed pictures of the insides of your body, such as a CT scan or magnetic resonance imaging (MRI)

If you have ulcers caused by H. pylori, you’ll need treatment to kill the germs, heal your stomach lining, and keep the sores from coming back, It usually takes 1 to 2 weeks of treatment to get better. Your doctor will probably tell you to take a few different types of drugs. The options include:

Antibiotics to kill the bacteria in your body, such as amoxicillin, clarithromycin ( Biaxin ), metronidazole ( Flagyl ), tetracycline ( Sumycin ), or tinidazole ( Tindamax ). You’ll most likely take at least two from this group.Drugs that reduce the amount of acid in your stomach by blocking the tiny pumps that produce it. They include dexlansoprazole ( Dexilant ), esomeprazole ( Nexium ), lansoprazole ( Prevacid ), omeprazole ( Prilosec ), pantoprazole ( Protonix ), rabeprazole ( Aciphex ), or vonoprazan/amoxicillin/clarithromycin (Voquezna). Bismuth subsalicylate, which may also help kill H. pylori along with your antibiotics Medicines that block the chemical histamine, which prompts your stomach to make more acid. These are cimetidine ( Tagamet ), famotidine Pepcid, Zantac 360 ), and nizatidine ( Axid ).

Your treatment could mean you’ll take 14 or more pills per day for a few weeks, which seems like a lot of medicine. But it’s really important to take everything that your doctor prescribes and to follow their instructions. If you don’t take antibiotics the right way, bacteria in your body can become resistant to them, which makes infections harder to treat.

Wash your hands after you use the bathroom and before you prepare or eat food. Teach your children to do the same.Avoid food or water that’s not clean.Don’t eat anything that isn’t cooked thoroughly.Avoid food served by people who haven’t washed their hands.

Though stress and spicy foods don’t cause ulcers, they can keep them from healing quickly or make your pain worse. Talk to your doctor about ways to manage your stress, improve your diet, and, if you smoke, how you can get help to quit. Most ulcers caused by H.

pylori will heal after a few weeks of treatment. If you’ve had one, you should avoid taking NSAIDs for pain, since these drugs can damage your stomach lining. If you need pain medicine, ask your doctor to recommend some. You can find information about H. pylori infection and ulcers from the American College of Gastroenterology,

For information on stomach cancer, as well as online and local support groups, visit the American Cancer Society,

Which fruit is good for H. pylori?

3. Fruits and vegetables – Non-acidic fruits and boiled vegetables should be eaten during the treatment of H. pylori because they are easily digested and help to improve bowel function. Certain fruits like raspberries, strawberries, blackberries and blueberries help to fight the growth of this bacteria, and therefore moderate intake can be considered.

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Are eggs OK with H. pylori?

Eggs provide many benefits to your body, and you should be able to eat them if you have a stomach ulcer. Stomach ulcers, also known as peptic ulcers, are open sores in the lining of your stomach. They most often develop from a bacterial infection from Heliobacter pylori ( H.

  • Pylori ) or from the overuse of nonsteroidal anti-inflammatory drugs (NSAIDs),
  • Your diet will not cure an already-existing ulcer, but eating a variety of healthy foods could help you heal and prevent future ulcers.
  • Avoid any foods or drinks that irritate your stomach and worsen your symptoms.
  • Eggs are not considered to be either good or bad for stomach ulcers,

There are many reasons to include eggs in your diet if they do not irritate your ulcer. The protein in eggs can contribute to your nutrition, muscle health, and feelings of fullness. Egg yolks are full of:

vitaminsnutrientsminerals antioxidants omega-3 fatty acids

Are bananas good for pylori?

Bananas – Both raw and ripe bananas are found to be very beneficial in curing stomach ulcer. There are certain antibacterial compounds in bananas that inhibit the growth of ulcer-causing H. pylori. Bananas are best to clear out the acidity of gastric juices that lowers the inflammation and strengthens the stomach lining.

Do bananas help with H. pylori?

Bacteria causes ulcers. – The bacteria h. pylori has been found to be culprit behind ulcers. Eating bananas prevent the h. pylori from breaking down the amino acids that it needs for survival.

Is yogurt good for pylori?

Tip – Fruits, vegetables, honey, tea and probiotic foods, such as yogurt and kefir, may help eradicate H. pylori infection and prevent complications. Make sure you also eat plenty of nuts, fatty fish and olive oil, which are loaded with omega-3s. These healthy fats inhibit bacteria growth and support digestive function.

Is Ginger good for Helicobacter pylori?

GINGER – Ginger root (Zingiber officinale) is traditionally designed for treating gastrointestinal ailments, i.e,, hyperemesis gravidarum, dyspepsia, peptic ulcer, motion sickness and inflammatory disorders. The proximate chemical composition of ginger contains volatile oils (1%-4%), medically active elements of ginger.

  1. Ginger employs anti-oxidant and anti-ulcer, anti-inflammatory, anti-tumor, carminative, diaphonic and digestive, expectorant actions.
  2. The phenols found in solvent extracts of ginger are mainly gingerol and zingerone.
  3. Siddaraju et al found that an aqueous extract of ginger can protect the gastric mucosa from stress-induced mucosal lesions and inhibit gastric acid secretion, which can be done by blocking H +, K + -ATPase action, thus restricting H.

pylori growth. Ginger produces anti-oxidant protection against oxidative stress-induced gastric damage, thus, exhibiting anti-oxidative properties in vitro, Li et al validated and strengthened the association between hyperemesis gravidarum (HG) and H.

Pylori infection in normal pregnant control subjects and pregnant women with HG. They found positive H. pylori in 1289 (69.6%) HG cases and 1045 (46.2%) H. pylori -positive in the control group. The infection rate of H. pylori was considerably higher in pregnant women with HG compared to the non-HG normal pregnant controls.

Analysis of a subgroup revealed that H. pylori infection was a risk factor of HG in other countries, i.e,, Oceania, Asia and especially Africa. Karaca et al stated that lower socio-economic status was an important risk factor for H. pylori infected pregnant women with an HG factor.

  • Other studies have found that certain agents active against H.
  • Pylori are very effective in the treatment of hyperemesis.
  • The human Chorionic Gonadotropin (hCG) when elevated in pregnancy, concurrently alters the pH in pregnancy.
  • HCG was found to induce gastrointestinal dysmotility, altered humoral as well as cell mediated immunity in pregnancy believed to be the basis for infection.

Several preclinical studies suggest that ginger, an agent linked to gastric and colon carcinogenesis, generates a protective effect against H. pylori, Ginger phenolic fractions provide inhibitory effects on the growth of H. pylori, scavenge free radicals, reduce power abilities, protect DNA and inhibit lipid peroxidation.

  • Mahady et al reported on the chemo-preventative effects of ginger which directly impede H.
  • Pylori growth, particularly CagA+ strains.
  • The authors showed that gingerols and ginger extracts inhibit the development of H.
  • Pylori in vitro of 19 clinical strains.
  • In addition, the fraction comprising the gingerols and 6-shogoal was very successful in inhibiting the growth of H.

pylori CagA+ strains. This documentation suggests that specific ginger extracts containing gingerols may assist in treating or preventing H. pylori CagA and strains in vivo, Researchers studying Mongolian gerbils noted that ginger extract prevented and treated H.

Can I eat apples with H. pylori?

Journal List Caspian J Intern Med v.8(2); Spring 2017 PMC5494052

As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health. Learn more: PMC Disclaimer | PMC Copyright Notice Caspian J Intern Med.2017 Spring; 8(2): 131–132.

Dear Editor, Helicobacter pylori (H. pylori) is a Gram-negative bacillus. Since its discovery in the early eighties by warren and marshall, for the first time in the history of medicine H. pylori was isolated from human gastric biopsy specimens ( 1 ). Many studies have presented that H. pylori can be isolated from the oral cavity and salivary secretions.

Colonization of the gastric pits in the stomach by this brachium is a serious risk factor for peptic ulcers and stomach cancer ( 2 ). Several antibiotic regimens have been assessed for H. pylori therapy. Despite that, few regimens have shown high eradication rates.

  1. Therapeutic regimens of H.
  2. Pylori infection are usually based on at least two types of antibiotics (imidazoles, macrolides and amoxicillin) combined with a double dose of the proton-pump inhibitor (omeprazole or pantoprazole).
  3. The problem of eradication therapy is the potentially undesirable increasing resistance of H.

pylori to the commonly used antibiotics. Moreover, eradication therapy is associated with some side effects. Long-term therapy with the antibiotic can result in pervasive alterations in gut flora and lead to susceptibility infections. So, the development of the adjuvant therapy for the eradication of H.

  • Pylori which also prevent adverse side effects would be a valuable item.
  • Accordingly, different potential adjuvant therapies for H.
  • Pylori have been considered.
  • The major research on alternative therapies contains foods like plant origin, probiotics, and polysaccharides.
  • Some compounds from medicinal plants with anti- H.pylori activity consist of polyphenolic, sulforaphane, flavonoids, carvacrol, tannins, quercetin and β-hydrastine ( 3, 4 ).

Green tea contains polyphenols, which hamper the growth of bacteria. Some studies have shown that drinking green tea can decrease H. pylori colonization during standard treatments ( 5 ). Broccoli sprouts (high in sulphorafane), cruciferous vegetables include kale, cabbage, cauliflower, brussels sprouts, red-headed cabbage, and radishes (high in isothiocyanates) can diminish the H.

Pylori growth ( 6 ). Apples contain flavonoids that defend the lining materials of the stomach against H.pylori infection ( 7 ). Honey exhibits potent in vitro bacteriostatic activity against H. pylori and inhibits urease activity. Antibacterial activity of honey is attributable to its hydrogen peroxide content ( 5 ).

Probiotic bacteria can modulate H. pylori activity by either immunological (reduction of IL-1 and IL-6) or non-immunological mechanisms (competition with potential microorganisms) ( 3 ). Therefore, the use of antibiotics as first-line therapies may be appropriate for the eradication of H.pylori, but the results confirm the medicinal properties of some foods and compounds as a new adjuvant therapy for H.pylori eradication.

Is drinking water good for H. pylori?

How Can I Prevent Getting Infected with H. Pylori? – Since the source of H. pylori is not yet known, it is difficult to list what should be avoided in order to prevent infection. In general, maintaining proper hygiene, eating food that has been properly prepared and drinking water from a safe, clean source will all help in preventing an infection from this or any other pathogenic bacteria.

Which tea is good for H. pylori?

Green tea had a significant bactericidal/lytic effect on H. felis and H. pylori (P

How long does Helicobacter pylori last?

Abstract – The existence of any infectious agent in a highly acidic human stomach is contentious, but the chance finding of Helicobacter pylori is by no means an accident. Once H. pylori colonises the gastric mucosa, it can persist for a lifetime, and it is intriguing why our immune system is able to tolerate its existence.

  • Some conditions favour the persistence of H.
  • Pylori in the stomach, but other conditions oppose the colonisation of this bacterium.
  • Populations with high and extremely low prevalence of H.
  • Pylori provide useful insights on the clinical outcomes that are associated with this type of infection.
  • Adverse clinical outcomes including peptic ulcer disease and gastric cancer depend on a delicate balance between a harmless inflammation and a more severe kind of inflammation.

Is the only good H. pylori really a dead H. pylori ? The jury is still out. Keywords: Helicobacter pylori, survival, elimination, gastric cancer, peptic ulcer disease, stomach

Is tea bad for Helicobacter pylori?

Green Tea and Flavonoid-Rich Foods – Emerging research from China shows the potential protective effects of green tea and other foods that are rich in flavonoids against chronic gastritis, H. pylori infection, and stomach cancer. Specifically, these foods seem to inhibit the growth of H.

pylori, In addition, one recent laboratory study of green, white, oolong, and black teas indicated that these teas inhibit the growth of H. pylori but cause no harm to beneficial types of bacteria normally found in the stomach, including L. acidophilus, L. plantarum, and B. lungum, However, this was an in vitro study, which means testing occurred directly between teas and bacteria in the laboratory, and we cannot draw direct conclusions as to what would happen inside the human body between these two substances.

Beneficial effects in the laboratory were best when tea steeped for a full five minutes. Flavonoid-rich foods include garlic, onions, and colourful fruits and vegetables such as cranberries, strawberries, blueberries, broccoli, carrots, and snap peas.4,5

Is chicken good for pylori?

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Prevalence, Virulence Genes, Phylogenetic Analysis, and Antimicrobial Resistance Profile of Helicobacter Species in Chicken Meat and Their Associated Environment at Retail Shops in Egypt. Foods 2022, 11, 1890. Mousavi, S.; Dehkordi, F.S. Virulence factors and antibiotic resistance of Helicobacter pylori isolated from raw milk and unpasteurized dairy products in Iran.J. Venom. Anim. Toxins Incl. Trop. Dis.2015, 20, 1–7. Yahaghi, E.; Khamesipour, F.; Mashayekhi, F.; Safarpoor Dehkordi, F.; Sakhaei, M.H.; Masoudimanesh, M.; Khameneie, M.K. Helicobacter pylori in vegetables and salads: Genotyping and antimicrobial resistance properties. BioMed Res. Int.2014, 2014, 757941. Li, J.; Deng, J.; Wang, Z.; Li, H.; Wan, C. Antibiotic resistance of Helicobacter pylori strains isolated from pediatric patients in Southwest China. Front. Microbiol.2020, 11, 621791. Sabbagh, P.; Mohammadnia-Afrouzi, M.; Javanian, M.; Babazadeh, A.; Koppolu, V.; Vasigala, V.R.; Nouri, H.R.; Ebrahimpour, S. 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Table 2. Prevalence of H. pylori in different types of raw poultry meat samples. Table 2. Prevalence of H. pylori in different types of raw poultry meat samples.

Raw Meat Samples No Samples Collected n (%) of H. pylori Positive Samples H. pylori 16SrRNA PCR Confirmation (%)
Chicken 60 9 (15.00) 9 (15.00)
Turkey 55 7 (12.72) 7 (12.72)
Quebec 65
Goose 65
Ostrich 75 4 (5.33) 4 (5.33)
Total 320 20 (6.25) (95%) 20 (6.25) (95%)

Table 3. Antibiotic resistance pattern of H. pylori strains isolated from different types of raw poultry meat samples. Table 3. Antibiotic resistance pattern of H. pylori strains isolated from different types of raw poultry meat samples.

Type of Raw Milk Samples (Number of H. pylori Strains) Number (%) Isolates Resistant to Each Antibiotic
AM10 a Met5 ER5 CLR2 AMX 10 Tet30 Lev5 S10 RIF30 Cef30 TRP25 FZL1 Spi100
Chicken (9) 8 (88.88) 6 (66.66) 4 (44.44) 4 (44.44) 7 (77.77) 7 (77.77) 3 (33.33) 2 (22.22) 3 (33.33) 2 (22.22) 3 (33.33) 2 (22.22) 3 (33.33)
Turkey (7) 5 (71.42) 2 (28.57) 3 (42.85) 2 (28.57) 5 (71.42) 7 (100) 2 (28.57) 7 (100) 4 (57.14) 4 (57.14) 3 (42.85) 3 (42.85) 3 (42.85)
Ostrich (4) 4 (100) 2 (50) 1 (25) 1 (25) 3 (75) 3 (75) 1 (25) 1 (25) 1 (25) 1 (25)
Total (20) 17 (85) 10 (50) 8 (40) 7 (35) 15 (75) 17 (85) 6 (30) 10 (50) 8 (40) 6 (30) 7 (35) 5 (25) 6 (30)

Table 4. Antimicrobial resistance profile of H. pylori strains ( n = 20). Table 4. Antimicrobial resistance profile of H. pylori strains ( n = 20).

No. Antimicrobial Resistance Profile MAR Index
1 AM10, Met5, ER5, CLR2, AMX10, Tet30, Lev5, S10, RIF30, Cef30, TRP25, FZL1, Spi100 1
2 AM10, Met5, ER5, CLR2, AMX10, Tet30, Lev5, S10, RIF30, Cef30, TRP25, FZL1, Spi100 1
3 AM10, Met5, ER5, CLR2, AMX10, Tet30, Lev5, S10, RIF30, Cef30, TRP25, FZL1 0.923
4 AM10, Met5, ER5, CLR2, AMX10, Tet30, Lev5, S10, RIF30, Cef30, TRP25, FZL1 0.923
5 AM10, Met5, ER5, CLR2, AMX10, Tet30, Lev5, S10, RIF30, Cef30, TRP25, FZL1 0.923
6 AM10, Met5, ER5, CLR2, AMX10, Tet30, Lev5, S10, RIF30, Cef30, TRP25 0.846
7 AM10, Met5, ER5, CLR2, AMX10, Tet30, Lev5, S10, RIF30, Cef30, TRP25 0.846
8 AM10, Met5, ER5, CLR2, AMX10, Tet30, Lev5, S10, RIF30, Cef30 0.769
9 AM10, Met5, ER5, CLR2, AMX10, Tet30, Lev5, S10, RIF30, Cef30 0.769
10 AM10, Met5, ER5, CLR2, AMX10, Tet30, Lev5, S10, RIF30, Cef30 0.769
11 AM10, Met5, ER5, CLR2, AMX10, Tet30, Lev5, S10, RIF30 0.692
12 AM10, Met5, ER5, CLR2, AMX10, Tet30, Lev5, S10 0.615
13 AM10, Met5, ER5, CLR2, AMX10, Tet30, Lev5, S10 0.615
14 AM10, Met5, ER5, CLR2, AMX10, Tet30, Lev5 0.538
15 AM10, Met5, ER5, CLR2, AMX10 0.384
16 AM10, Met5, ER5, CLR2 0.307
17 AM10, Met5, ER5 0.230
18 AM10, Met5 0.153
19 AM10 0.076
20 AM10 0.076
Average 0.622

Table 5. Distribution of genotypes amongst the H. pylori strains isolated from different types of raw poultry meat samples. Table 5. Distribution of genotypes amongst the H. pylori strains isolated from different types of raw poultry meat samples.

Type of Raw Milk Samples (Number of H. pylori Strains) Number (%) Isolates Harbor Each Genotype
VacA CagA IceA OipA BabA2
s1a s1b s1c s2 m1a m1b m2 IceA1 IceA2
Chicken (9) 7 (77.77) 3 (33.33) 1 (11.11) 6 (66.66) 7 (77.77) 3 (33.33) 6 (66.66) 6 (66.66) 4 (44.44) 2 (22.22) 3 (33.33) 4 (44.44)
Turkey (7) 6 (85.71) 2 (28.57) 6 (85.71) 6 (85.71) 1 (14.28) 5 (71.42) 5 (71.42) 3 (42.85) 1 (14.28) 2 (28.57) 3 (42.85)
Ostrich (4) 2 (50) 2 (50) 2 (50) 1 (25) 2 (50) 1 (25) 1 (25) 1 (25)
Total (20) 15 (75) 5 (25) 1 (5) 14 (70) 15 (75) 5 (25) 13 (65) 12 (60) 8 (40) 3 (15) 5 (25) 8 (40)

Table 6. Genotyping pattern of H. pylori strains isolated from different types of raw poultry meat samples. Table 6. Genotyping pattern of H. pylori strains isolated from different types of raw poultry meat samples.

Type of Raw Milk Samples (Number of H. pylori Strains) Genotyping Pattern (%)
s1am1a s1am1b s1am2 s1bm1a s1bm1b s1bm2 s1cm1a s1cm1b s1cm2 s2m1a s2m1b s2m2 CagA+ CagA− IceA1/IceA2 OipA+ OipA− BabA2+ BabA2−
Chicken (9) 5 (55.55) 2 (22.22) 4 (44.44) 2 (22.22) 1 (11.11) 2 (22.22) 1 (11.11) 1 (11.11) 4 (44.44) 2 (22.22) 3 (33.33) 6 (66.66) 3 (33.33) 1 (11.11) 3 (33.33) 6 (66.66) 4 (44.44) 5 (55.55)
Turkey (7) 3 (42.85) 1 (14.28) 1 (14.28) 1 (14.28) 1 (14.28) 3 (42.85) 1 (14.28) 2 (28.57) 3 (42.85) 2 (28.57) 1 (14.28) 2 (28.571) 1 (14.28) 2 (28.57)
Ostrich (4) 1 (25) 2 (50) 1 (25) 1 (25) 1 (25) 1 (25)
Total (20) 9 (45) 3 (15) 5 (25) 3 (15) 2 (10) 2 (10) 1 (5) 1 (5) 9 (45) 3 (15) 6 (30) 10 (5) 5 (25) 2 (10) 6 (30) 6 (30) 5 (25) 8 (40)


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What destroys Helicobacter pylori?

1. Introduction – In the 1980s, Marshall and Warren first discovered Helicobacter pylori ( H. pylori ) in the stomach of patients with gastritis, peptic ulceration or active chronic gastritis, which subsequently aroused significant attention in the scientific and medical community ( Warren and Marshall, 1983 ; Marshall and Warren, 1984 ).

Helicobacter pylori has been established to be a Gram-negative spiral pathogen within the gastric mucus layer or attached to the gastric epithelial cells, infecting approximately 4.4 billion people worldwide ( Hooi et al., 2017 ). The prevalence of H. pylori infection is associated with socioeconomic status, level of urbanization, environmental sanitation, access to clean water and personal hygiene.

Meanwhile, higher prevalence has been reported in developing countries than in developed countries ( Yan et al., 2013 ; Hooi et al., 2017 ). Helicobacter pylori infection usually occurs during childhood and develops into chronic progressive gastritis throughout life.

  1. About 1–10% of infected individuals have clinical symptoms, including peptic ulcer disease, gastric atrophy, and intestinal metaplasia of gastric mucosa, which eventually lead to gastric cancer or mucosa-associated lymphoid tissue (MALT) lymphoma ( Tshibangu-Kabamba and Yamaoka, 2021 ). Thus, H.
  2. Pylori is considered an infectious disease regardless of the clinical symptoms of the infected person ( Sugano et al., 2015 ).

Helicobacter pylori is classified as a gastric adenocarcinoma Group I carcinogen by the International Agency for Research on Cancer ( IARC Working Group, 1994 ). On December 21, 2021, the US Department of Health and Human Services (HHS) released the 15th edition of the Carcinogenic Report, which listed H.

pylori as a Class I carcinogen ( U.S. Department of Health and Human Services, 2021 ). Therefore, the eradication of H. pylori is essential. The Kyoto Consensus pointed out that all people infected with H. pylori should receive eradication therapy unless there are other special circumstances, such as comorbidities or local reinfection ( Sugano et al., 2015 ).

According to the Maastricht VI/Florence consensus report, eradicating H. pylori before the stage of chronic atrophic gastritis can cure both gastritis and peptic ulcers, thereby preventing gastric cancer ( Malfertheiner et al., 2022 ). At present, the methods to eradicate H.

  1. Pylori infection clinically are still limited to antibiotic-based therapies ( Tshibangu-Kabamba and Yamaoka, 2021 ).
  2. Both the American College of Gastroenterology (ACG) Guidelines and the Toronto Consensus recommend bismuth-based quadruple therapy with a combination of proton pump inhibitor (PPI), clarithromycin, amoxicillin, and metronidazole as the first-line regimen ( Fallone et al., 2016 ; Chey et al., 2017 ).

The main antibiotics used clinically to eradicate H. pylori are amoxicillin, fluoroquinolones, rifampin, tetracycline, clarithromycin and metronidazole ( Lai et al., 2022 ). Amoxicillin acts on the penicillin-binding proteins (PBPs) of the bacteria, which will interfere with the synthesis of the bacterial cell wall and cause the bacteria to rupture and dissolve.

Fluoroquinolones can interact with bacterial DNA topoisomerases, causing irreversible damage to their chromosomes and stopping the cell division of bacteria. Rifampicin can inhibit bacterial RNA polymerase, thus blocking the process of RNA transcription and the synthesis of DNA and protein. Tetracyclines inhibit the synthesis of protein by binding to the 30S subunit of bacterial intracellular ribosomes.

And clarithromycin binds to the 50S subunit of bacterial ribosomes, to hinder the synthesis of protein ( Guimaraes et al., 2010 ; Baquero and Levin, 2021 ). Although the bactericidal mechanism of metronidazole has not been fully elucidated, it is generally accepted that the drug acts by the reduced nitro group ( Alauzet et al., 2019 ).

  1. Considering the mechanisms leading to the failure of H.
  2. Pylori eradication, antibiotic resistance is currently the main reason.
  3. The antibiotic resistance of H.
  4. Pylori presents three characteristics: single drug resistance, multi-drug resistance and heterogeneous drug resistance ( Tshibangu-Kabamba and Yamaoka, 2021 ).

Secondly, stomach acid can affect the effectiveness of antibiotics. For example, amoxicillin is easily degraded by stomach acid, which requires a high dose for treatment and resulting the failure of eradication due to its side effects ( Zhu et al., 2022 ).

The morphology of H. pylori can also affect its eradication. The coccoid forms of H. pylori can evade detection by the immune system and lead to the failure of antibiotic treatment ( Krzyżek and Grande, 2020 ). Finally, the formation of biofilms can lead to the failure of H. pylori eradication as well ( Moghadam et al., 2021 ).

In 2014, the antibiotic resistance had been listed as one of the three major threats to public health in the 21st century by the World Health Organization ( Munita and Arias, 2016 ). Researches show that antibiotic resistance causes more than 7 million deaths annually worldwide, including 25,000–33,000 and 23,000 deaths in European and the United States, respectively ( Baquero, 2021 ).

According to the prediction of the World Health Organization, 10 million people may die due to the increase of antibiotic resistance by 2050 ( Pulingam et al., 2022 ). Meanwhile, all-age mortality from antibiotic resistance is highest in some low-and middle-income countries and poses the greatest threat to human health in sub-Saharan Africa and South Asia ( Murray et al., 2022 ).

A review of antibiotic resistance in H. pylori shows that the global eradication rate of H. pylori has been declining and the increasing antibiotic resistance associated with H. pylori ( Thung et al., 2016 ). The eradication rate of empirical H. pylori treatment has fallen below the target of 80–90%, with failure rates of 29 and 40% in the United States and Western Europe respectively, and clarithromycin resistance rates of approximately 30% in Japan and up to 50% in China ( Thung et al., 2016 ).H.

Pylori has been listed as one of the 20 most dangerous pathogens to human health by the World Health Organization (WHO) in 2017 ( Tacconelli et al., 2018 ). Therefore, it is imperative to develop alternative therapies to eradicate H. pylori, especially those resistant to multiple antibiotics. This review discussed colonization of H.

pylori in the stomach and its virulence mechanism. Besides, the methods of non-pharmacological treatment of H. pylori are summarized, which provides a new treatment prospect for overcoming the problem of drug resistance of H. pylori in the future.

Is it OK to eat bananas with H. pylori?

Bananas – Both raw and ripe bananas are found to be very beneficial in curing stomach ulcer. There are certain antibacterial compounds in bananas that inhibit the growth of ulcer-causing H. pylori. Bananas are best to clear out the acidity of gastric juices that lowers the inflammation and strengthens the stomach lining.

Is egg bad for Helicobacter pylori?

As a nutritional supplement, Egg Yolk Antibody (Ig Y) provides a new approach for H. pylori infection rescue therapy.

What is the best thing to drink with H. pylori?

What is the best thing to drink for an ulcer? – A person may benefit from drinking drinks that contain antioxidants which may help combat H. pylori infections, such as cranberry juice. A person may also benefit from drinking drinks that contain probiotics, such as kombucha.

  1. Stomach ulcers are sores that form on the lining of the stomach or duodenum.
  2. They can be caused by a bacterial infection or by taking NSAIDs.
  3. There are a number of drinks that may help soothe stomach ulcers, including green cabbage juice, kombucha, honey water, and turmeric tea.
  4. These drinks all have anti-inflammatory or antioxidant properties that can help protect the stomach lining.

Some drinks individuals may want to avoid when experiencing stomach ulcers include alcohol and coffee. These drinks can irritate the stomach lining and increase acid production. In addition to lifestyle changes, medical treatments are available for stomach ulcers.